Endocrine Abstracts

Aim: Triple-A Syndrome (TAS) is a rare autosomal recessive disorder characterized by three cardinal symptoms: alacrimia, achalasia and adrenal insufficiency due to ACTH insensitivity. The disease is caused by mutation in the AAAS gene on chromosome 12q13. Mutations in AAAS were identified in more than 90% of individuals and families with TAS. The aim of this study is to discuss the clinical, laboratory and molecular genetic analysis results of 5 patients with TAS.<p class=...

Introduction: The incidence of papillary thyroid cancer (PTC) in the coexistence of Graves’ disease (GD) and thyroid nodule is not known clearly, and the pathophysiology of PTC development in these patients is still unclear. Aim: The aim of our study is to compare the clinicopathological features of GD patients with thyroid nodule + PTC and patients with euthyroid and non auto-immune thyroid nodule + PTC and investigate the clinicopathological featu...

Background: Hypophysitis is a rare group of disease characterized with infla mmation of the pituitary gland. Rarity of the disease obviates development of a treatment strategy. We aimed to present the nationwide data of the demographics, clinical and radiological characteristics, treatment modalities and responses of the patients diagnosed with hypophysitis in a retrospective manner.Methods: The endocrinology clinics all over the country were invited to ...